Problems with alcohol? 29 gene variants may explain why
By the 1980s investigators traced the reaction to an enzyme involved in alcohol metabolism, aldehyde dehydrogenase, and eventually to the gene that encodes it, ALDH1. The enzyme breaks down acetaldehyde, but slight variations in the gene’s DNA code in these subjects caused the enzyme to work more slowly. When these individuals ingested alcohol, the acetaldehyde–which […]
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